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Anti-LRP6 Rabbit Monoclonal Antibody

Anti-LRP6 Rabbit Monoclonal Antibody

ArtNr	BOS-M00970-30ul
Hersteller	Boster
Menge	30 ul
Quantity options	100 ul/vial 30 ul
Kategorie	Oncology Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism Antibodies By Cell Type Obesity Flow Cytometry Western Blot Immunofluorescence Immunocytochemistry Lipoprotein Receptors & Associated Proteins Primary Antibodies Immunochemistry
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, FC, IF, ICC
Clon	21L27
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Sensitivity	<10 pg/ml
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Nuclear factor of activated T-cells,cytoplasmic 2,NF-ATc2,NFATc2,NFAT pre-existing subunit,NF-ATp,T-cell transcription factor NFAT1,NFATC2,NFAT1,NFATP
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Manufacturer - Category	Primary Antibodies, Rabbit Monoclonal Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Molecular Weight	230 kDa
Calculated Molecular weight	100146 MW
Clonality	Monoclonal
Application Details	WB 1:500-1:2000 ICC/IF 1:50-1:200 FC 1:50
Gene Name	LRP6
Gene Full Name	Nuclear factor of activated T-cells, cytoplasmic 2
Immunogen	A synthesized peptide derived from human LRP6
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA.
Purification	Affinity-chromatography
Reconstitution	Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration	Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category	Adaptive Immunity, Cytokines, Epigenetics and Nuclear Signaling, Immunology, Innate Immunity, Nuclear Signaling, Nuclear Signaling Pathways, Signal Transduction, Signaling Pathway
Protein Name	Glycogen synthase kinase-3 beta (gsk3b)
Protein Function	Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2, IL-3, IL-4, TNF-alpha or GM-CSF. Promotes invasive migration through the activation of GPC6 expression and WNT5A signaling pathway.
Subcellular Localization	Cytoplasm. Nucleus. Cytoplasmic for the phosphorylated form and nuclear after activation that is controlled by calcineurin-mediated dephosphorylation. Rapid nuclear exit of NFATC is thought to be one mechanism by which cells distinguish between sustained and transient calcium signals. The subcellular localization of NFATC plays a key role in the regulation of gene transcription.
Description	Boster Bio Anti-LRP6 Rabbit Monoclonal Antibody catalog # M00970. Tested in WB, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Expressed in thymus, spleen, heart, testis, brain, placenta, muscle and pancreas. Isoform 1 is highly expressed in the small intestine, heart, testis, prostate, thymus, placenta and thyroid. Isoform 3 is highly expressed in stomach, uterus, placenta, trachea and thyroid.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

BOS-M00970-30ul-datasheet.pdf

BOS-M00970-30ul-safety-datasheet.pdf