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Anti-ADK Antibody Picoband® (monoclonal, 7F4) Europäischer Partner

ArtNr BOS-M02193-10ug
Hersteller Boster
Menge 10 ug
Format Lyophilized
Applikationen WB, FC, IHC
Clon 7F4
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG1
Sensitivity >5000 cells
Citations 1. Boison D, Scheurer L, Zumsteg V, Rulicke T, Litynski P, Fowler B, Brandner S, Mohler H: Neonatal hepatic steatosis by disruption of the adenosine kinase gene. Proc Natl Acad Sci U S A 2002, 99: 6985-6990.
2. Fox IH, Kelley WN: The role of adenosine and 2'-deoxyadenosine in mammalian cells. Annu Rev Biochem 1978, 47: 655-686.
Alias Adenosine kinase; AK; Adenosine 5'-phosphotransferase; ADK
Lieferbar
Manufacturer - Category
Primary Antibodies
Manufacturer - Isotype
Mouse IgG1
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
45 kDa
Clonality
Monoclonal
Application Details
Western blot, 0.1-0.5?g/ml

Immunohistochemistry (Paraffin-embedded Section), 0.5-1?g/ml

Flow Cytometry (Fixed), 1-3?g/1x106 cells
Manufacturer - Gene Name
ADK
Gene Full Name
adenosine kinase
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
This gene is an enzyme which catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen
E. coli-derived human ADK recombinant protein (Position: K165-T351). Human ADK shares 88.8% and 88.2% amino acid (aa) sequence identity with mouse and rat ADK, respectively.
Contents
Each vial contains 4 mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05 mg NaN3.
Purification
Immunogen affinity purified.
Reconstitution
Add 0.2 ml of distilled water will yield a concentration of 500 µg/ml.
Manufacturer - Research Category
DNA/RNA, Epigenetics and Nuclear Signaling, Ribosome, RNA Processing, Translation
Protein Name
Mitofusin-1
Protein Function
ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives. Serves as a potential regulator of concentrations of extracellular adenosine and intracellular adenine nucleotides.
Subcellular Localization
Nucleus. Cytoplasm.
Description
Boster Bio Anti-ADK Antibody Picoband® (monoclonal, 7F4) catalog # M02193. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity
Widely expressed. Highest level in placenta, liver, muscle and kidney.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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