ArtNr |
BOS-M02193-10ug |
Hersteller |
Boster
|
Menge |
10 ug |
Format |
Lyophilized |
Applikationen |
WB, FC, IHC |
Clon |
7F4 |
Specific against |
Human (Homo sapiens) |
Host |
Mouse |
Isotype |
IgG1 |
Sensitivity |
>5000 cells |
Citations |
1. Boison D, Scheurer L, Zumsteg V, Rulicke T, Litynski P, Fowler B, Brandner S, Mohler H: Neonatal hepatic steatosis by disruption of the adenosine kinase gene. Proc Natl Acad Sci U S A 2002, 99: 6985-6990. 2. Fox IH, Kelley WN: The role of adenosine and 2'-deoxyadenosine in mammalian cells. Annu Rev Biochem 1978, 47: 655-686. |
Alias |
Adenosine kinase; AK; Adenosine 5'-phosphotransferase; ADK |
Lieferbar |
|
Manufacturer - Category |
Primary Antibodies |
Manufacturer - Isotype |
Mouse IgG1 |
Storage Conditions |
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. |
Observed Molecular Weight |
45 kDa |
Clonality |
Monoclonal |
Application Details |
Western blot, 0.1-0.5?g/ml
Immunohistochemistry (Paraffin-embedded Section), 0.5-1?g/ml
Flow Cytometry (Fixed), 1-3?g/1x106 cells |
Manufacturer - Gene Name |
ADK |
Gene Full Name |
adenosine kinase |
Manufacturer - Specificity |
No cross reactivity with other proteins. |
Background |
This gene is an enzyme which catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Multiple transcript variants encoding different isoforms have been found for this gene. |
Immunogen |
E. coli-derived human ADK recombinant protein (Position: K165-T351). Human ADK shares 88.8% and 88.2% amino acid (aa) sequence identity with mouse and rat ADK, respectively. |
Contents |
Each vial contains 4 mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05 mg NaN3. |
Purification |
Immunogen affinity purified. |
Reconstitution |
Add 0.2 ml of distilled water will yield a concentration of 500 µg/ml. |
Manufacturer - Research Category |
DNA/RNA, Epigenetics and Nuclear Signaling, Ribosome, RNA Processing, Translation |
Protein Name |
Mitofusin-1 |
Protein Function |
ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives. Serves as a potential regulator of concentrations of extracellular adenosine and intracellular adenine nucleotides. |
Subcellular Localization |
Nucleus. Cytoplasm. |
Description |
Boster Bio Anti-ADK Antibody Picoband® (monoclonal, 7F4) catalog # M02193. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance. |
Tissue Specificity |
Widely expressed. Highest level in placenta, liver, muscle and kidney. |
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