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Anti-ADK Antibody Picoband® (monoclonal, 7F4)

Anti-ADK Antibody Picoband® (monoclonal, 7F4)

Item no.	BOS-M02193-10ug
Manufacturer	Boster
Amount	10 ug
Format	Lyophilized
Applications	WB, FC, IHC
Clone	7F4
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
Sensitivity	>5000 cells
Citations	1. Boison D, Scheurer L, Zumsteg V, Rulicke T, Litynski P, Fowler B, Brandner S, Mohler H: Neonatal hepatic steatosis by disruption of the adenosine kinase gene. Proc Natl Acad Sci U S A 2002, 99: 6985-6990. 2. Fox IH, Kelley WN: The role of adenosine and 2'-deoxyadenosine in mammalian cells. Annu Rev Biochem 1978, 47: 655-686.
Alias	Adenosine kinase; AK; Adenosine 5'-phosphotransferase; ADK
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Isotype	Mouse IgG1
Storage Conditions	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	45 kDa
Clonality	Monoclonal
Application Details	Western blot, 0.1-0.5?g/ml Immunohistochemistry (Paraffin-embedded Section), 0.5-1?g/ml Flow Cytometry (Fixed), 1-3?g/1x10⁶ cells
Manufacturer - Gene Name	ADK
Gene Full Name	adenosine kinase
Manufacturer - Specificity	No cross reactivity with other proteins.
Background	This gene is an enzyme which catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen	E. coli-derived human ADK recombinant protein (Position: K165-T351). Human ADK shares 88.8% and 88.2% amino acid (aa) sequence identity with mouse and rat ADK, respectively.
Contents	Each vial contains 4 mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05 mg NaN3.
Purification	Immunogen affinity purified.
Reconstitution	Add 0.2 ml of distilled water will yield a concentration of 500 µg/ml.
Manufacturer - Research Category	DNA/RNA, Epigenetics and Nuclear Signaling, Ribosome, RNA Processing, Translation
Protein Name	Mitofusin-1
Protein Function	ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives. Serves as a potential regulator of concentrations of extracellular adenosine and intracellular adenine nucleotides.
Subcellular Localization	Nucleus. Cytoplasm.
Description	Boster Bio Anti-ADK Antibody Picoband® (monoclonal, 7F4) catalog # M02193. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity	Widely expressed. Highest level in placenta, liver, muscle and kidney.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 ug

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Delivery expected until 7/3/2025

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