Vergleich

Biotinylated Human Nectin-2 / CD112 Protein, His,Avitag™ (MALS verified) Europäischer Partner

Hersteller ACROBiosystems
Kategorie
Typ Proteins
Specific against Human
Format Powder
Menge 25ug
ArtNr CD2-H82E7-25ug
Konjugat/Tag His Tag & Avi Tag
eClass 6.1 34160400
eClass 9.0 42020190
Lieferbar
Bioactivity Legend 1
Immobilized Biotinylated Human Nectin-2, His, Avitag (Cat. No. CD2-H82E7) at 1 μg/mL (100 μL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate can bind Human PVRIG, Fc Tag (Cat. No. PVG-H5257) with a linear range of 0.6-10 ng/mL (QC tested).
Bioactivity Legend 2
Immobilized Biotinylated Human Nectin-2, His, Avitag (Cat. No. CD2-H82E7) at 1 μg/mL (100 μL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate can bind Human DNAM-1, Fc Tag (Cat. No. DN1-H5257) with a linear range of 0.039-0.625 μg/m
Buffer
PBS, pH7.4
Characteristics
This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 39.1 kDa. The protein migrates as 45-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Description
Poliovirus receptor-related 2 (PVRL2) is also known as nectin-2 and CD112 (formerly herpesvirus entry mediator B, HVEB), which is a human plasma membrane glycoprotein. PVRL2 is one of the plasma membrane components of adherens junctions. PVRL2 also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in PVRL2 gene have been associated with differences in the severity of multiple sclerosis. Also, PVRL2 binds with low affinity to TIGIT. Furthermore, PVRL2 acts as a receptor for herpes simplex virus 1 (HHV-1) mutant Rid1, herpes simplex virus 1 (HHV-2) and pseudorabies virus (PRV).
Endotoxin Level
Less than 1.0 EU per μg by the LAL method.
Exp Region
Gln 32 - Leu 360
Expression System
HEK293
Molecular Weight
39.1 kDa
Molecule
Nectin-2
SDS-PAGE Legend
Biotinylated Human Nectin-2, His, Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Storage
-20℃

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 25ug
Lieferbar: In stock
lieferbar

Lieferung vsl. bis 18.04.2024 

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