MCC950

ArtNr	HY-12815-25mg
Hersteller	MedChem Express
CAS-Nr.	210826-40-7
Menge	25 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 1 ea 1 mg 25 mg 500 ug 50 mg 5 mg
Kategorie	Oncology Neuroscience Metabolism Diabetes Glucose Homeostasis Aging & Neurological Disorders Inhibitors & Compound Libraries Small Molecules By Organ Bone Cancer
Typ	Inhibitors
Specific against	other
Purity	99.62
Citations	[1]Coll RC, et al. A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases. Nat Med. 2015 Mar;21(3):248-55. 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Smiles	O=S(C1=CC(C(C)(O)C)=CO1)(NC(NC2=C3CCCC3=CC4=C2CCC4)=O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	CP-456773,CRID3
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	NOD-like Receptor (NLR)
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	404.48
Product Description	MCC950 (CP-456773; CRID3) is a potent and selective NLRP3 inhibitor with IC50s of 7.5 and 8.1 nM in BMDMs and HMDMs, respectively.
Manufacturer - Research Area	Inflammation/Immunology
Solubility	DMSO: 83.33 mg/mL (ultrasonic)\|H2O: 7.14 mg/mL (ultrasonic; warming; adjust pH to 11 with 1 M NaOH)
Manufacturer - Pathway	Immunology/Inflammation
Isoform	NLRP3
Clinical information	No Development Reported

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HY-12815-25mg-safety-datasheet.pdf