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Human NKp44 / NCR2 / CD336 Protein, Llama IgG2b Fc Tag, low endotoxin

Human NKp44 / NCR2 / CD336 Protein, Llama IgG2b Fc Tag, low endotoxin

ArtNr	NC2-H5258-100ug
Hersteller	ACROBiosystems
Menge	100 ug
Quantity options	100 ug 250 ug x 4
Kategorie	Peptides & Proteins Amino Acids
Typ	Proteins
Format	Solid
Specific against	Human (Homo sapiens)
Host	HEK293
Konjugat/Tag	Unconjugated
Purity	90%
NCBI	NP_004819.2
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Natural cytotoxicity triggering receptor 2,NKp44,NCR2,CD336,LY95
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Category	Protein / Bio-Markers & CD Antigens
Manufacturer - Conjugate / Tag	C-LlamaFc(LlamaIgG2b), Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	46.5 kDa
Manufacturer - Format	Powder
Description	Human NKp44, Llama IgG2b Fc Tag (NC2-H5258) is expressed from human 293 cells (HEK293). It contains AA Gln 22 - Ala 192 (Accession # O95944-1).
Background	NKp44, a member of Natural Cytotoxicity Receptors (NCRs), is an activating receptor playing a crucial role in most functions exerted by activated NK cells and also by other NKp44+ immune cells. Membrane-associated PCNA is a ligand for the NKp44 (NCR2) innate immune receptorMembrane-associated PCNA is a ligand for the NKp44 (NCR2) innate immune receptor. NKp44 / NCR2 / CD336 may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
Molecule	NKp44
Exp Region	Gln 22 - Ala 192
Characteristics	This protein carries a llama IgG2b Fc tag at the C-terminus. The protein has a calculated MW of 46.5 kDa. The protein migrates as 55-65 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	0.01 EU per μg
Buffer	50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5
Stability	● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

NC2-H5258-100ug-datasheet.pdf

NC2-H5258-100ug-safety-datasheet.pdf