sCD40L

ArtNr	cyt-245-10ug
Hersteller	ProSpec
Menge	10 ug
Quantity options	10 ug 1 mg 50 ug
Kategorie	Neuroscience Neural Lineage Markers Neuroinflammation Metabolism Diabetes Glucose Homeostasis Aging & Neurological Disorders Peptides & Proteins Recombinant Proteins
Typ	Cytokines and Growth Factors
Format	Lyophilized
Specific against	Human (Homo sapiens)
Purity	Greater than 97.0% as determined by:<BR>(a) Analysis by RP-HPLC.<BR>(b) Analysis by SDS-PAGE.
ECLASS 10.1	42030690
ECLASS 11.0	42030690
UNSPSC	12352202
Alias	sCD40L,CD40-L,Tumor necrosis factor ligand superfamily member 5,TNF-related activation protein,TRAP,T cell antigen Gp39,CD154 antigen,sCD40,IGM,IMD3,HIGM1,T-BAM,TNFSF5,hCD40L
Similar products	sCD40L
Lieferbar
Manufacturer - Category	CYTOKINES AND GROWTH FACTORS
Storage Conditions	Lyophilized sCD40 although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution CD154 should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Description	Recombinant Human soluble CD40 Ligand/TRAP
Formulation	Lyophilized from a0.2um filtered concentrated (1mg/ml) solution in PBS, pH 7.0.
Introduction	CD40L or CD154 is a membrane glycoprotein and differentiation antigen expressed on the surface of T-cells. The CD40 ligand stimulates B-cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines . CD40 ligand has been shown to induce cytokine production and tumoricidal activity in peripheral blood monocytes. It also costimulates proliferation of activated T-cells and this is accompanied by the production of IFN-gamma , TNF-alpha , and IL2 .
Usage	ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Biological Activity	The ED50 as determined by the dose-dependant stimulation of IL-12 induction IL-8 production by human PBMC was found to be 5-10 ng/ml.
Manufacturer - Format	Sterile Filtered White lyophilized (freeze-dried) powder.

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cyt-245-10ug-safety-datasheet.pdf