Leptin tA PEG

ArtNr	cyt-702-20ug
Hersteller	ProSpec
Menge	20 ug
Quantity options	1 mg 20 ug 5 ug
Kategorie	Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Peptides & Proteins Recombinant Proteins
Typ	Cytokines and Growth Factors
Format	Lyophilized
Specific against	Human (Homo sapiens)
Purity	Greater than 98.0% as determined by: <BR>(a) Gel filtration analysis. <BR>(b) Analysis by SDS-PAGE.
ECLASS 10.1	42030690
ECLASS 11.0	42030690
UNSPSC	12352202
Alias	Leptin tA PEG
Similar products	Leptin tA PEG
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Manufacturer - Category	CYTOKINES AND GROWTH FACTORS
Storage Conditions	Lyophilized PEG-SHLA although stable at room temperature for several weeks, should be stored desiccated below - 20C. Upon reconstitution at 0.1 mg/ml and up to 2 mg/ml of PEG-SHLA and filter sterilization mLEP mutant can be stored at 4C or even room temperature for several weeks making it suitable for long term infusion studies using osmotic pumps. At lower concentration addition of a carrier protein (0.1% HSA or BSA) is suggested. Please prevent freeze-thaw cycles.
Description	Recombinant Pegylated Human Leptin Triple Antagonist
Formulation	The protein was lyophilized from a concentrated (0.65mg/ml) solution with 0.003mM NaHCO3.
Usage	ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Biological Activity	Capable of inhibiting leptin-induced proliferation of BAF/3 cells stably transfected with the long form of human leptin receptor. Its in vitro activity is 6-8 fold lower than the non-pegylated antagonist but in vivo it has profound weight gain effect (as compared to the non-pegylated antagonist), resulting mainly from increased food intake. Its in vivo activity compared to that of PEG-MLA is 9-27 fold higher.
Manufacturer - Format	White lyophilized (freeze-dried) powder.

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cyt-702-20ug-safety-datasheet.pdf