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Recombinant Human Nanog-TAT

Recombinant Human Nanog-TAT

Hersteller	ProSpec
Kategorie	Neuroscience Neural Lineage Markers Metabolism Diabetes Glucose Homeostasis Neural Transcription Factors Peptides & Proteins Recombinant Proteins Calcium Binding Protein Markers
Typ	Proteins
Specific against	Human
Menge	5ug
ArtNr	pro-090-5ug
eClass 6.1	34160400
eClass 9.0	42020190
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Synonyms	NANOG, Homeobox protein NANOG, Homeobox transcription factor Nanog, hNanog
Introduction	NANOG is a multidomain homeobox transcription factor which functions to maintain the undifferentiated state of pluripotent stem cells. NANOG expression counteracts the differentiation-promoting signals induced by the extrinsic factors LIF, Stat3 and BMP. Once NANOG expression is downregulated, cell differentiation can proceed. Proteins which regulate NANOG expression include transcription factors Oct4, SOX2, FoxD3, and Tcf3 and tumor suppressor p53.
Description	NANOG Human Recombinant produced in E.Coli is a single, non-glycosylated, Polypeptide chain containing 305 amino acids and having a molecular mass of 34.6kDa. The NANOG is fused to an N-terminal TAT (transcriptional activator protein) tag and purified by proprietary chromatographic techniques.
Source	Escherichia Coli.
Physical Appearance	Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation	NANOG was lyophilized after extensive dialysis against PBS.
Purity	Greater than 95.0% as determined by: (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.
Usage	ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Amino acid sequence	The sequence of the first five N-terminal amino acids was determined and was found to be Met-Gly-Arg-Lys-Lys.
Storage	Lyophilized NANOG although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution NANOG should be stored at 4C between 2-7 days and for future use below -18C. Please prevent freeze-thaw cycles.

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pro-090-5ug-safety-datasheet.pdf