Hersteller |
ProSpec
|
Kategorie |
|
Typ |
Proteins |
Specific against |
Human |
Menge |
1ug |
ArtNr |
pro-1330-1ug |
eClass 6.1 |
34160400 |
eClass 9.0 |
42020190 |
Lieferbar |
|
Synonyms |
Protein amnionless, AMN, PRO1028, amnionless |
Introduction |
Amnion Associated Transmembrane Protein (AMN) is a type I transmembrane protein. The AMN protein is essential for efficient absorption of vitamin B12. AMN is assumed to modulate bone morphogenetic protein (BMP) receptor function by acting as an accessory or coreceptor thus facilitating or hindering BMP binding. A complex of AMN and cubilin forms the cubam receptor. |
Description |
AMN Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 361 amino acids (20-357 a.a) and having a molecular mass of 38.2kDa. AMN is fused to a 23 amino acid His-tag at N-terminus purified by proprietary chromatographic techniques. |
Source |
Escherichia Coli. |
Physical Appearance |
Sterile Filtered colorless solution. |
Formulation |
AMN protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.1M NaCl, 10% glycerol and 1mM DTT. |
Purity |
Greater than 90.0% as determined by SDS-PAGE. |
Usage |
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
Amino acid sequence |
MGSSHHHHHH SSGLVPRGSH MGS VSKLWVP NTDFDVAANW SQNRTPCAGG AVEFPADKMV SVLVQEGHAV SDMLLPLDGE LVLASGAGFG VSDVGSHLDC GAGEPAVFRD SDRFSWHDPH LWRSGDEAPG LFFVDAERVP CRHDDVFFPP SASFRVGLGP GASPVRVRSI SALGRTFTRD EDLAVFLASR AGRLRFHGPG ALSVGPEDCA DPSGCVCGNA EAQPWICAAL LQPLGGRCPQ AACHSALRPQ GQCCDLCGAV VLLTHGPAFD LERYRARILD TFLGLPQYHG LQVAVSKVPR SSRLREADTE IQVVLVENGP ETGGAGRLAR ALLADVAENG EALGVLEATM RESGAHVWGS S. |
Storage |
Store at 4C if entire vial will be used within 2-4 weeks. Store, frozen at -20C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.