SERPINA1, Active

ArtNr	pro-907-100ug
Hersteller	ProSpec
Menge	100 ug
Quantity options	100 ug 1 mg 20 ug
Kategorie	Food Safety Proteins Peptides & Proteins Recombinant Proteins
Typ	Proteins
Format	Lyophilized
Specific against	Human (Homo sapiens)
Purity	Greater than 95% as determined by SDS-PAGE.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	SERPINA1,Active,Alpha-1-antitrypsin,Alpha-1 protease inhibitor,Alpha-1-antiproteinase,SERPINA1,A1AT,PI,A1A,AAT,PI1,MGC9222,PRO2275,MGC23330
Similar products	SERPINA1, Active
Lieferbar
Manufacturer - Category	RECOMBINANT & NATURAL PROTEINS
Storage Conditions	Lyophilized SERPINA1 although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution SERPINA1 should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Description	Recombinant Human Alpha-1 Antitrypsin, Active
Formulation	SERPINA1 was lyophilized from a concentrated solution containing recombinant Albumin.
Introduction	SERPINA1 is secreted and is a serine protease inhibitor which its targets include elastase, plasmin, collagenase, thrombin, leucocytic proteases, trypsin, chymotrypsin, and plasminogen activator. Defects in SERPINA1 gene can cause emphysema or liver disease. Antral SERPINA1 expression is particularly induced by H. pylori infection. lung and prostate cancers have shown a significant increase in SERPINA1 serum levels compared with healthy controls though breast cancers did not show a significant change. SERPINA1 is an endogenous inhibitor of serine proteases and inhibits the catalytic domain of human recombinant matriptase in vitro. Rise in SERPINA1 occurs as an acute phase response to tissue necrosis and inflammation. mutations in SERPINA1 and SLC11A1 genes change the balance between elastase produced by leukocytes during phagocytosis.
Usage	ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Biological Activity	3ca.5 mg SERPINA1 will inhibit 1 mg PPE with an activity of 10.8 units per mg protein
Manufacturer - Format	Sterile Filtered White lyophilized (freeze-dried) powder.

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pro-907-100ug-safety-datasheet.pdf