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Recombinant Streptokinase

Recombinant Streptokinase

ArtNr	enz-315-1.5MIU
Hersteller	ProSpec
Menge	1.5MIU
Kategorie	Peptides & Proteins Enzymes
Typ	Enzymes
Specific against	other
ECLASS 10.1	32160410
ECLASS 11.0	32160410
UNSPSC	12352204
Similar products	Streptokinase
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Synonyms	Streptokinase, SK
Introduction	Streptokinase is an extracellular metallo-enzymeproduced by beta-haemolytic streptococcusand is used as an effective and cheap clot-dissolving medicationin some cases of myocardial infarction(heart attack) and pulmonary embolism. It belongs to a group of medications known as fibrinolytics, and works by activating plasminogenthrough cleavage to produce plasmin.
Description	Streptokinase Recombinant produced in E.Coli is a non-glycosylated polypeptide chain containing 414 amino acids and having a molecular weight of 47kDa. The Streptokinase is purified by proprietary chromatographic techniques.
Source	Escherichia Coli.
Physical Appearance	Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation	Lyophilized from a0.2um filtered concentrated (1mg/ml) solution in PBS, pH 7.4.
Purity	Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Usage	ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Biological Activity	The specific biological activity measured by the ability of fibrin lysis in agarose plate was found to be 80000U/mg.
Storage	Lyophilized Streptokinase although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution Streptokinase should be stored at 4C between 2-7 days and for future use below -18C. Please prevent freeze-thaw cycles.

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enz-315-1.5MIU-safety-datasheet.pdf