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Recombinant Streptokinase

Recombinant Streptokinase

Item no.	enz-315-1.5MIU
Manufacturer	ProSpec
Amount	1.5MIU
Category	Peptides & Proteins Enzymes
Type	Enzymes
Specific against	other
ECLASS 10.1	32160410
ECLASS 11.0	32160410
UNSPSC	12352204
Similar products	Streptokinase
Available
Synonyms	Streptokinase, SK
Introduction	Streptokinase is an extracellular metallo-enzymeproduced by beta-haemolytic streptococcusand is used as an effective and cheap clot-dissolving medicationin some cases of myocardial infarction(heart attack) and pulmonary embolism. It belongs to a group of medications known as fibrinolytics, and works by activating plasminogenthrough cleavage to produce plasmin.
Description	Streptokinase Recombinant produced in E.Coli is a non-glycosylated polypeptide chain containing 414 amino acids and having a molecular weight of 47kDa. The Streptokinase is purified by proprietary chromatographic techniques.
Source	Escherichia Coli.
Physical Appearance	Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation	Lyophilized from a0.2um filtered concentrated (1mg/ml) solution in PBS, pH 7.4.
Purity	Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Usage	ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Biological Activity	The specific biological activity measured by the ability of fibrin lysis in agarose plate was found to be 80000U/mg.
Storage	Lyophilized Streptokinase although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution Streptokinase should be stored at 4C between 2-7 days and for future use below -18C. Please prevent freeze-thaw cycles.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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enz-315-1.5MIU-safety-datasheet.pdf