Human FGF1/FGF acidic protein

Cytokine

FGF1/aFGF

Lyophilized Human FGF1/FGF acidic proteinshould be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.98% HSA or BSA). Please prevent freeze-thaw cycles.

FGF1, also known as FGF acidic, ECGF, aFGF and HBGF-1, is a nonglycosylated member of the FGF family of mitogenic peptides. FGF1, which is produced by multiple cell types, stimulates the proliferation of all cells of mesodermal origin and many cells of neuroectodermal, ectodermal, and endodermal origin. FGF1 protein shows a wide range of endocrine-like activities. As a multiple function growth factor, this protein is involved in embryo development and tissue repair. Additionally, this protein is considered to function in several important physiological and pathological processes, such as embryonic development, morphogenesis, angiogenesis, wound healing and atheromatosis, carcinogenesis, development, and invasion of cancer.

Lyophilized from sterile 20mM tris, 50mM NaCl, pH 6.5.

Endotoxin: < 1.0 EU per µg of the protein as determined by the LAL method.

E. coli

The recombinant Human FGF1/FGF acidic protein consists of 140 amino acids and has a predicted molecular mass of 15.5 KD.