Human VEGF165 protein

Cytokine

VEGFA

Lyophilized Human VEGF165 proteinshould be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.62% HSA or BSA). Please prevent freeze-thaw cycles.

Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family and often exists as a disulfide-linked homodimer. VEGF-A protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, inhibiting apoptosis and tumor growth. VEGF-A protein is also a vasodilator that increases microvascular permeability, thus it was originally referred to as vascular permeability factor.

Lyophilized from sterile 100 mM Glycine, 10 mM NaCl, pH 7.0.

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Human VEGF165 protein in sterile ddH2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Measured in a cell proliferation assay using human umbilical vein endothelial cells (HUVEC). The ED50 for this effect is typically 4-16 ng/mL.
The ED50 for this effect is typically 4-16 ng/mL.

MVCD1, VEGF, VEGF165, VPF, Vascular endothelial growth factor A, VEGFA