Rat IL-1β protein

Cytokine

IL-1β

Lyophilized Rat IL-1β proteinshould be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.19% HSA or BSA). Please prevent freeze-thaw cycles.

Interleukin-1β (IL-1β or IL-1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL-1β is a proinflammatory cytokine produced in a variety of cells, including monocytes, tissue macrophages, keratinocytes, and other epithelial cells. IL-1β is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by Interleukin 1β in the central nervous system (CNS). IL-1β gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

Lyophilized from sterile 20mM Tris, 0.15M NaCl, pH 7.4.

Endotoxin: < 1.0 EU per µg of the protein as determined by the LAL method.

E. coli

The recombinant Rat IL-1β consists of 152 amino acids and has a predicted molecular mass of 17.4 KDa.