Recombinant SARS-CoV-2 Spike RBD Protein, His tag (Animal-Free)

Cytokine

SARS-CoV-2 Spike RBD

Lyophilized Recombinant SARS-CoV-2 Spike RBD Protein, His tag (Animal-Free)should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.121% HSA or BSA). Please prevent freeze-thaw cycles.

COVID-19 has become pandemic with higher morbidity and mortality rates after its start from Wuhan city of China. The infection by RNA virus, also known as SARS-CoV-2 or 2019-nCoV, from β class of corona viruses has been found to be responsible for COVID-19. Structural analysis and evidences have been indicated that interaction between a segment of receptor binding domain (RBD) from S protein of virus and human angiotensin-converting enzyme 2 (hACE2) is essential for cellular entry of virus. Inhibition of RBD-hACE2 interaction by different molecular scaffolds can be used as a preferred strategy for control of SARS-CoV-2 infection.

Lyophilized from sterile PBS, pH 7.4.

Endotoxin: < 1 EU per µg of the protein as determined by the LAL method.

HEK293 Cells

The recombinant SARS-CoV-2 (COVID-19) Spike RBD protein consists of 229 amino acids and predicts a molecular mass of 26.5 kD.The apparent molecular mass of the human CD33 is approximately 32-35 kDa in SDS-PAGE under reducing conditions due to glycosylation.