Mouse IL-4 protein (Animal-Free)

Interleukin-4 is a pleiotropic cytokine produced primarily by activated T lymphocytes, basophils and mast cells. It is a glycosylated polypeptide that contains three intrachain disulfide bridges and adopts a bundled four alpha -helix structure.It plays an important role in the treatment and research of tumor and autoimmune diseases, in addition to its role in mediating inflammatory allergic reaction. Mouse IL-4 is synthesized with a 24 aa signal sequence.Multiple immune response-modulating functions are performed by IL-4 on a variety of cell types and it has an important role in the regulator of isotype switching, induction of IgE production in B lymphocytes and differentiation of precursor T helper cells. IL-4 binds to both membrane-bound and secreted soluble IL-4 receptors.

IL-4; Interleukin 4; BCGF1; BSF1

IL-4

Amino acid sequence derived from mouse IL-4 (P07750) (Met 1-Ser140) was expressed with a 6His tag at the C-terminus.

HEK293 Cells

0.22 um filtered protein solution is in PBS.

15-19 kDa

Lyophilized mouse IL-4 protein product should be stored desiccated below -20CC. Upon reconstitution, the protein should be stored at 4CC between 2-7 days and for future use below -20CC. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.