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Mouse ADAM9 Protein, His Tag (active enzyme, MALS verified) Europäischer Partner

ArtNr AD9-M52H3-50ug
Hersteller ACROBiosystems
Menge 50 ug
Quantity options 500 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Specific against Mouse (Murine, Mus musculus)
Host HEK293
Source Mouse ADAM9, His Tag (AD9-M52H3) is expressed from human 293 cells (HEK293). It contains AA Ala 206 - Asp 697 (Accession # Q61072).
Konjugat/Tag Unconjugated
Purity 95%
Dry ice Yes
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Versandbedingung Trockeneis
Lieferbar
Manufacturer - Category
Protein
Manufacturer - Conjugate / Tag
C-10xHis, Unconjugated
Shipping Temperature
Dry ice
Storage Conditions
-70°C
Molecular Weight
55.2 kDa
Manufacturer - Format
Liquid
Description
ADAM9 (A disintegrin and a metalloprotease 9) is a membrane-anchored protein that participates in a variety of physiological functions, primarily through the disintegrin domain for adhesion and the metalloprotease domain for ectodomain shedding of a wide variety of cell surface proteins. ADAM9 influences the developmental process, inflammation, and degenerative diseases.Recently, increasing evidence has shown that ADAM9 plays an important role in tumor biology. Overexpression of ADAM9 has been found in several cancer types and is correlated with tumoraggressiveness and poor prognosis. In addition, through either proteolytic or non-proteolytic pathways, ADAM9 promotes tumor progression, therapeutic resistance, and metastasis of cancers.
Background
ADAM9 (A disintegrin and a metalloprotease 9) is a membrane-anchored protein that participates in a variety of physiological functions, primarily through the disintegrin domain for adhesion and the metalloprotease domain for ectodomain shedding of a wide variety of cell surface proteins. ADAM9 influences the developmental process, inflammation, and degenerative diseases.Recently, increasing evidence has shown that ADAM9 plays an important role in tumor biology. Overexpression of ADAM9 has been found in several cancer types and is correlated with tumoraggressiveness and poor prognosis. In addition, through either proteolytic or non-proteolytic pathways, ADAM9 promotes tumor progression, therapeutic resistance, and metastasis of cancers.
Molecule
ADAM9
Exp Region
Ala 206 - Asp 697
Characteristics
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 55.2 kDa. The protein migrates as 70-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
25mM MES, 150mM NaCl, pH6.0
Stability
● The product MUST be stored at -70°C or lower upon receipt
● -70°C for 3 months under sterile conditions.
Protectant
glycerol

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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