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Cynomolgus APRIL / TNFSF13 Protein, His,Flag Tag, active trimer (MALS verified) Europäischer Partner

ArtNr APL-C52D2-100ug
Hersteller ACROBiosystems
Menge 100 ug
Quantity options 100 ug 1 mg
Kategorie
Typ Proteins Recombinant
Format Solid
Specific against Monkey (Cynomolgus, Simian)
Host HEK293
Konjugat/Tag Unconjugated, FLAG
Purity 95%
NCBI XP_005582818.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias APRIL,TNFSF13,TALL-2,TRDL-1,CD256,TALL2,ZTNF2
Versandbedingung Raumtemperatur
Lieferbar
Specificity Cynomolgus
Manufacturer - Category
Protein
Manufacturer - Conjugate / Tag
N-10xHis & N-Flag, Unconjugated
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
50.4 kDa
Manufacturer - Format
Powder
Description
Cynomolgus APRIL, His, Flag Tag (APL-C52D2) is expressed from human 293 cells (HEK293). It contains AA Gln 111 - Leu 250 (Accession # XP_005582818.1) trimer Design.
Background
APRIL(a proliferation-inducing ligand) is also known as Tumor necrosis factor ligand superfamily member 13, TALL-2, TRDL-1, CD256, TNFFSF 13, cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. APRIL is a cytokine of the tumor necrosis factor family associated mainly with hematologic malignancies. The closely related TNF family ligands B cell activation factor (BAFF) and a proliferation-inducing ligand (APRIL) serve in the generation and maintenance of mature B-lymphocytes. Both BAFF and APRIL assemble as homotrimers that bind and activate several receptors that they partially share. BAFF-APRIL heteromers of different stoichiometries have distinct receptor-binding properties and activities. In addition, expression of APRIL was regulated by miR-145 in GC cells.
Molecule
APRIL
Exp Region
Gln 111 - Leu 250
Characteristics
This protein carries a polyhistidine tag at the N-terminus, followed by a flag tag. The protein has a calculated MW of 50.4 kDa. The protein migrates as 55-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
PBS, pH7.4
Stability
● -20°C to -70°C for 12 months in lyophilized state
● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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