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Biotinylated Human B7-H3 / CD276 Protein, Avitag™,His Tag Europäischer Partner

ArtNr B73-H82E6-25ug
Hersteller ACROBiosystems
Menge 25 ug
Quantity options 200 ug 25 ug
Kategorie
Typ Proteins Recombinant
Format Solid
Specific against Human (Homo sapiens)
Host HEK293
Konjugat/Tag Biotin, HIS, Avi
Purity 95%
Citations (1) Chapoval A.I., et al., 2001, Nat. Immunol. 2:269-274. (2) Castriconi R., et al., 2004, Proc. Natl. Acad. Sci. U.S.A. 101:12640-12645. (3) Wang L., et al., 2005, Eur. J. Immunol. 35:428-438.
NCBI NP_079516.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias B7-H3,CD276,B7 homolog 3
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Category
Protein / MABSol® Biotin Labeled Proteins
Manufacturer - Conjugate / Tag
C-Avi & C-10xHis, Biotin-labeled
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
26.5 kDa
Manufacturer - Format
Powder
Description
Biotinylated Human B7-H3 Protein, Avitag, His Tag (B73-H82E6) is expressed from human 293 cells (HEK293). It contains AA Leu 29 - Pro 245 (Accession # Q5ZPR3-2).
Background
B7 homolog 3 (B7-H3), a member of the immunoglobulin superfamily, is also known CD276, which contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domains. B7-H3 may participate in the regulation of T-cell-mediated immune response. B7-H3 also plays a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. Furthermore, B7-H3 is involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. It could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy.
Molecule
B7-H3
Exp Region
Leu 29 - Pro 245
Characteristics
This protein carries an Avi tag (Avitag™) at the C-terminus, followed by a polyhistidine tag. The protein has a calculated MW of 26.5 kDa. The protein migrates as 35-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
PBS, pH 7.4
Stability
● -20°C to -70°C for 12 months in lyophilized state;
● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 25 ug
Lieferbar: In stock
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