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Human B7-H5 / Gi24 / VISTA Protein, Mouse IgG2a Fc Tag, low endotoxin Europäischer Partner

ArtNr B75-H5258-1mg
Hersteller ACROBiosystems
Menge 500 ug x 2
Quantity options 100 ug 500 ug x 2
Kategorie
Typ Proteins Recombinant
Format Solid
Specific against Human (Homo sapiens)
Host HEK293
Isotype IgG2a
Konjugat/Tag Unconjugated, C-mFc
Purity 95%
Citations (1) Sakr M.A., et al., 2010, Cancer Sci. 101:2368-2374. (2) Mayya V., et al ., 2009, Sci. Signal. 2:RA46-RA46.
NCBI AAH20568.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias B7-H5,SISP1,Gi24,VISTA
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Category
Protein / Immune Checkpoint Proteins
Manufacturer - Conjugate / Tag
C-mFc(mIgG2a), Unconjugated
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
45.0 kDa
Manufacturer - Format
Powder
Description
Human B7-H5 Protein, Mouse IgG2a Fc Tag (B75-H5258) is expressed from human 293 cells (HEK293). It contains AA Phe 33 - Ala 194 (Accession # AAH20568.1).
Background
Platelet receptor Gi24, also known as B7-H5 and stress-induced secreted protein-1 (Sisp-1), is a protein that in humans is encoded by the C10orf54 gene, which contains 1 Ig-like (immunoglobulin-like) domain. As for C10orf54 gene, C10orf54 appears to positively interact with BMP-4, potentiating BMP signaling and the transition from an undifferentiated to a differentiated state on ESCs. Human C10orf54 undergoes proteolytic cleavage by MT1-MMP, generating a soluble 30 kDa extracellular fragment plus a 25-30 kDa membrane-bound fragment.
Molecule
B7-H5
Exp Region
Phe 33 - Ala 194
Characteristics
This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 45.0 kDa. The protein migrates as 55-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
0.1 EU per μg
Buffer
50 mM Tris, 100 mM Glycine, pH 7.5
Stability
● -20°C to -70°C for 12 months in lyophilized state;
● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug x 2
Lieferbar: In stock
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