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Cynomolgus / Rhesus macaque BCMA / TNFRSF17 Protein, His Tag (HPLC verified)

Cynomolgus / Rhesus macaque BCMA / TNFRSF17 Protein, His Tag (HPLC verified)

ArtNr	BCA-C52H7-1mg
Hersteller	ACROBiosystems
Menge	500 ug x 2
Quantity options	100 ug 500 ug x 2
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Solid
Specific against	Monkey (Cynomolgus, Simian), Rhesus macaque
Host	HEK293
Konjugat/Tag	Unconjugated
Purity	90%
Citations	(1) Hatzoglou A., et al., 2000, J. Immunol. 165:1322-1330. (2) Gross J.A., et al., 2000, Nature 404:995-999. (3) Yu G., et al., 2000, Nat. Immunol. 1:252-256.
NCBI	XP_005591343.1
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	TNFRSF17,CD269,BCM,BCMA
Versandbedingung	Raumtemperatur
Lieferbar
Specificity	Cynomolgus / Rhesus macaque
Manufacturer - Category	Protein
Manufacturer - Conjugate / Tag	C-10xHis, Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	7.9 kDa
Manufacturer - Format	Powder
Description	Cynomolgus / Rhesus macaque BCMA, His Tag (BCA-C52H7) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 53 (Accession # A0A2K5UD97-1). In the region Met 1 - Ala 53, the AA sequence of Cynomolgus and Rhesus macaque BCMA are homologus.
Background	Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.
Molecule	BCMA
Exp Region	Met 1 - Ala 53
Characteristics	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 7.9 kDa. The protein migrates as 13-14 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	PBS, pH7.4
Stability	● -20°C to -70°C for 12 months in lyophilized state ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

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BCA-C52H7-1mg-datasheet.pdf

BCA-C52H7-1mg-safety-datasheet.pdf