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Human BCMA / TNFRSF17 Protein, Mouse IgG2a Fc Tag, low endotoxin (MALS verified)

Human BCMA / TNFRSF17 Protein, Mouse IgG2a Fc Tag, low endotoxin (MALS verified)

ArtNr	BCA-H5253-100ug
Hersteller	ACROBiosystems
Menge	100 ug
Quantity options	100 ug 500 ug x 2
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Solid
Specific against	Human (Homo sapiens)
Host	HEK293
Isotype	IgG2a
Konjugat/Tag	Unconjugated, C-mFc
Purity	90%
Citations	(1) Hatzoglou A., et al., 2000, J. Immunol. 165:1322-1330. (2) Gross J.A., et al., 2000, Nature 404:995-999. (3) Yu G., et al., 2000, Nat. Immunol. 1:252-256.
NCBI	NP_001183.2
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	TNFRSF17,CD269,BCM,BCMA
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Category	Protein
Manufacturer - Conjugate / Tag	C-mFc(mIgG2a), Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	32.8 kDa
Manufacturer - Format	Powder
Description	Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.
Background	Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.
Molecule	BCMA
Exp Region	Met 1 - Ala 54
Characteristics	This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 32.8 kDa. The protein migrates as 35-42 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	0.01 EU per μg
Buffer	Tris with Glycine, Arginine and NaCl, pH7.5
Stability	● -20°C to -70°C for 12 months in lyophilized state ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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BCA-H5253-100ug-datasheet.pdf

BCA-H5253-100ug-safety-datasheet.pdf