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FITC-Labeled Human BCMA / TNFRSF17 Protein, Fc Tag Europäischer Partner

ArtNr BCA-HF254-200ug
Hersteller ACROBiosystems
Menge 200 ug
Quantity options 200 ug 25 ug
Kategorie
Typ Proteins Recombinant
Format Solid
Specific against Human (Homo sapiens)
Host HEK293
Konjugat/Tag FITC, Fc
Purity 92%
Citations (1) Hatzoglou A., et al., 2000, J. Immunol. 165:1322-1330. (2) Gross J.A., et al., 2000, Nature 404:995-999. (3) Yu G., et al., 2000, Nat. Immunol. 1:252-256.
NCBI NP_001183.2
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias TNFRSF17,CD269,BCM,BCMA
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Category
Protein
Manufacturer - Conjugate / Tag
C-Fc, FITC Labeled
Shipping Temperature
RT
Storage Conditions
-20°C, avoid light
Molecular Weight
31.97 kDa
Manufacturer - Format
Powder
Description
FITC-Labeled Human BCMA, Fc Tag (Cat. No. BCA-HF254) is expressed from human HEK293 cells. It contains AA Met 1 - Ala 54 (Accession # Q02223-1). It is the FITC labeled form of Human BCMA, Fc Tag (Cat. No. BC7-H5254).
Background
Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.
Molecule
BCMA
Exp Region
Met 1 - Ala 54
Characteristics
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 31.97 kDa. The protein migrates as 35-44 kDa under reducing (R) condition, and 60-75 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
PBS, pH7.4
Stability
● -20°C to -70°C for 12 months in lyophilized state
● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 200 ug
Lieferbar: In stock
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