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Human CCR5 Protein, Flag,His Tag (Detergent)

Human CCR5 Protein, Flag,His Tag (Detergent)

ArtNr	CC5-H52D1-20ug
Hersteller	ACROBiosystems
Menge	20 ug
Quantity options	100 ug 20 ug 500 ug
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Liquid
Specific against	Human (Homo sapiens)
Host	HEK293
Konjugat/Tag	Unconjugated, FLAG
Purity	85%
Dry ice	Yes
Citations	(1) M Samson. et al., 1996, Biochemistry 19;35(11):3362-7. (2) C Blanpain. et al., 2001, J Biol Chem 29;276(26):23795-804. (3) Einat Schnur. et al., 2001, J Mol Biol 29;410(5):778-97.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CCR5,CMKBR5,CD195,CC-CKR-5,CHEMR13
Versandbedingung	Trockeneis
Lieferbar
Manufacturer - Category	Protein
Manufacturer - Conjugate / Tag	N-Flag & C-10xHis, Unconjugated
Shipping Temperature	Dry ice
Storage Conditions	-70°C
Molecular Weight	46.0 kDa
Manufacturer - Format	Liquid
Description	Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation.5 Publications (Microbial infection) Acts as a coreceptor (CD4 being the primary receptor) of human immunodeficiency virus-1/HIV-1.
Background	Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation.5 Publications (Microbial infection) Acts as a coreceptor (CD4 being the primary receptor) of human immunodeficiency virus-1/HIV-1.
Molecule	CCR5
Exp Region	Asp 2 - Arg 223 & Glu 227 - Arg 319
Characteristics	This protein carries a flag tag at the N-terminus and a polyhistidine tag at the C-terminus. The protein has a calculated MW of 46.0 kDa. The protein migrates as 40-43 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).
Endotoxin	1.0 EU per μg
Buffer	50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5
Stability	● The product MUST be stored at -70°C or lower upon receipt ● -70°C for 3 months under sterile conditions.
Protectant	glycerol

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

CC5-H52D1-20ug-datasheet.pdf

CC5-H52D1-20ug-safety-datasheet.pdf