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Cynomolgus CD3E&CD3G/CD3 epsilon&CD3 gamma Protein (CD3-CM102)

ArtNr CD3-CM102-500UG
Hersteller KactusBio
Menge 500 ug
Quantity options 100 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Lyophilized
Specific against Monkey (Cynomolgus, Simian)
Host HEK293
Konjugat/Tag FLAG, HIS
Purity > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Formula Supplied as 0.22μm filtered solution in PBS (pH 7.4).
Sequence Gln22-Asp117 (CD3E) & Gln23-Thr113 (CD3G)
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias CD3,CD3 epsilon,CD3epsilon,CD3ε,CD3 ε,CD3E,CD3e,CD3 gamma,CD3gamma,CD3γ,CD3 γ,CD3G,CD3g,CD3epsilon&CD3gamma,CD3 epsilon&CD3 gamma,CD3 epsilon & CD3 gamma,CD3ε&CD3γ,CD3 ε&CD3 γ,CD3 ε & CD3 γ,CD3E&CD3G,CD3E & CD3G,CD3 E & CD3 G,CD3e&CD3g,CD3e & CD3g,CD3 e & CD3 g
Versandbedingung Raumtemperatur
Lieferbar
Specificity Cynomolgus
Manufacturer - Type
Recombinant Protein
Manufacturer - Targets
CD3E&CD3G/CD3 epsilon&CD3 gamma
Manufacturer - Conjugate / Tag
C-His-Flag
Shipping Temperature
Shipped at ambient temperature.
Storage Conditions
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Molecular Weight
The protein has a predicted MW of 11.93 kDa (CD3E) and 11.52 kDa (CD3G). Due to glycosylation, the protein migrates to 13-23 kDa based on Bis-Tris PAGE result.
Description
Recombinant Cynomolgus CD3E&CD3G/CD3 epsilon&CD3 gamma Protein is expressed from HEK293 with His tag at the C-Terminus of CD3E and Flag tag at the C-Terminus of CD3G.It contains Gln22-Asp117(CD3E) and Gln23-Thr113(CD3G).
Background
T-cell surface glycoprotein CD3 epsilon&CD3 gamma chain, also known as CD3E&CD3G, are single-pass type I membrane proteins. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain.
Endotoxin
Less than 1 EU per μg by the LAL method.
Formulation
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Biotinylated
no

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
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