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Human CD24 Protein, Fc Tag Europäischer Partner

ArtNr CD4-H5254-100ug
Hersteller ACROBiosystems
Menge 100 ug
Quantity options 100 ug 1 mg
Kategorie
Typ Proteins Recombinant
Format Solid
Specific against Human (Homo sapiens)
Host HEK293
Konjugat/Tag Unconjugated, Fc
Purity 95%
Citations (1) Suzuki T1, et al. 2001. J Immunol. 166(9):5567-77. (2) Chen Z, et al. 2017. Biomed Pharmacother. 90:427-436. (3) Eyvazi S, et al. 2018. Curr Cancer Drug Targets. 18(4):328-336.
NCBI NP_001278666.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias CD24,CD24A
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Category
Protein / Other Recombinant Proteins
Manufacturer - Conjugate / Tag
C-Fc, Unconjugated
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
29.6 kDa
Manufacturer - Format
Powder
Description
Human CD24, Fc Tag (CD4-H5254) is expressed from human 293 cells (HEK293). It contains AA Ser 27 - Gly 59 (Accession # P25063-1).
Background
CD24 may have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells. In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. Plays a role in the control of autoimmunity.
Molecule
CD24
Exp Region
Ser 27 - Gly 59
Characteristics
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 29.6 kDa. The protein migrates as 40-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
PBS, pH 7.4
Stability
● -20°C to -70°C for 12 months in lyophilized state;
● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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