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FITC-Labeled Human CD4 Protein, His Tag Europäischer Partner

ArtNr CD4-HF2H7-25ug
Hersteller ACROBiosystems
Menge 25 ug
Quantity options 100 ug x 2 25 ug
Kategorie
Typ Proteins Recombinant
Format Solid
Specific against Human (Homo sapiens)
Host HEK293
Konjugat/Tag FITC
Purity 95%
Citations (1) Brady RL, et al., 1993, Science 260 (5110): 979-83. (2) Zeitlmann, L., et al., 2001, J. Biol. Chem. (United States) 276 (12): 9123-32. (3) Rudd CE, et al., 2010, J. Immunol. 185 (5): 2645-9. (4) Rudd CE, et al., 1988, Proc. Natl. Acad. Sci. U.S.A. 85 (14): 5190-4. (5) Gorska MM, et al., 2004, J. Exp. Med. 199 (3): 369-79.
NCBI AAH25782
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias CD4,CD4mut,LEU3
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Category
Protein
Manufacturer - Conjugate / Tag
C-6xHis, FITC Labeled
Shipping Temperature
RT
Storage Conditions
-20°C, avoid light
Molecular Weight
41.5 kDa
Manufacturer - Format
Powder
Description
FITC-Labeled Human CD4, His Tag (CD4-HF2H7) is expressed from human 293 cells (HEK293). It contains AA Lys 26 - Trp 390 (Accession # AAH25782). It is the FITC labeled form of Human CD4, His Tag (LE3-H5228).
Background
T-cell surface glycoprotein CD4 is also known as T-cell surface antigen T4/Leu-3. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is accessory protein for MHC class-II antigen/T-cell receptor interaction. CD4 induces the aggregation of lipid rafts. CD4 is a primary receptor used by HIV-1 to gain entry into host T cells. HIV infection leads to a progressive reduction of the number of T cells possessing CD4 receptors. Therefore, medical professionals refer to the CD4 count to decide when to begin treatment for HIV-infected patients.
Molecule
CD4
Exp Region
Lys 26 - Trp 390
Characteristics
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 41.5 kDa. The protein migrates as 45-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
PBS, pH7.4
Stability
● -20°C to -70°C for 12 months in lyophilized state
● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 25 ug
Lieferbar: In stock
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