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Mouse CD27 / TNFRSF7 Protein, Mouse IgG2a Fc Tag, low endotoxin (MALS verified) Europäischer Partner

ArtNr CD7-M5252-100ug
Hersteller ACROBiosystems
Menge 100 ug
Quantity options 100 ug 200 ug x 5
Kategorie
Typ Proteins Recombinant
Format Solid
Specific against Mouse (Murine, Mus musculus)
Host HEK293
Isotype IgG2a
Konjugat/Tag Unconjugated, C-mFc
Purity 95%
Citations (1) Zhang Z., et al., 2004, Protein Sci. 13:2819-2824. (2) Gravestein L.A., et al., 1998, Eur. J. Immunol. 28:2208-2216. (3) Prasad K.V.S., et al., 1997, Proc. Natl. Acad. Sci. U.S.A. 94:6346-6351.
NCBI NP_001028298.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias CD27,TNFRSF7,S152,T14,Tp55
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Category
Protein
Manufacturer - Conjugate / Tag
C-mFc(mIgG2a), Unconjugated
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
45.1 kDa
Manufacturer - Format
Powder
Description
CD Antigen CD27 is also known as Tumor necrosis factor receptor superfamily member 7 (TNFRSF7), which belongs to TNF-receptor superfamily. CD27 / TNFRSF7 is found in most T-lymphocytes. CD27 / TNFRSF7 is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-κB and MAPK8/JNK. CD27 has been shown to interact with SIVA1, TRAF2 and TRAF3.
Background
CD Antigen CD27 is also known as Tumor necrosis factor receptor superfamily member 7 (TNFRSF7), which belongs to TNF-receptor superfamily. CD27 / TNFRSF7 is found in most T-lymphocytes. CD27 / TNFRSF7 is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-κB and MAPK8/JNK. CD27 has been shown to interact with SIVA1, TRAF2 and TRAF3.
Molecule
CD27
Exp Region
Thr 21 - Arg 182
Characteristics
This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 45.1 kDa. The protein migrates as 55-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
0.01 EU per μg
Buffer
Tris with Glycine, Arginine and NaCl, pH7.5
Stability
● -20°C to -70°C for 12 months in lyophilized state
● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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