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FITC-Labeled Human CD38 Protein, Fc Tag Europäischer Partner

ArtNr CD8-HF255-200ug
Hersteller ACROBiosystems
Menge 200 ug
Quantity options 200 ug 25 ug
Kategorie
Typ Proteins Recombinant
Format Solid
Specific against Human (Homo sapiens)
Host HEK293
Konjugat/Tag FITC, Fc
Purity 90%
Citations (1) Orciani M., et al., 2008, J. Cell. Biochem. 105 (3): 905-12. (2) Nata K., et al., 1997, Gene 186 (2): 285-92. (3) Malavasi F., et al., 2008, Physiol. Rev. 88 (3): 841-86.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias CD38,T10,cADPr hydrolase 1
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Category
Protein
Manufacturer - Conjugate / Tag
C-Fc, FITC Labeled
Shipping Temperature
RT
Storage Conditions
-20°C, avoid light
Molecular Weight
56.5 kDa
Manufacturer - Format
Powder
Description
FITC-Labeled Human CD38, Fc Tag (Cat. No. CD8-HF255) is expressed from human HEK293 cells. It contains AA Val 43 - Ile 300 (Accession # P28907-1). It is the FITC labeled form of Human CD38 Protein, Fc Tag (Cat. No. CD8-H5255).
Background
CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2+. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia.
Molecule
CD38
Exp Region
Val 43 - Ile 300
Characteristics
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 56.5 kDa. The protein migrates as 65-75 under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
PBS, pH7.4
Stability
● -20°C to -70°C for 12 months in lyophilized state
● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 200 ug
Lieferbar: In stock
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