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Rhesus macaque / Cynomolgus Complement Factor D / CFD Protein, His Tag (active enzyme) Europäischer Partner

ArtNr CFD-R52H3-1mg
Hersteller ACROBiosystems
Menge 1 mg
Quantity options 100 ug 1 mg
Kategorie
Typ Proteins Recombinant
Format Solid
Specific against Monkey (Cynomolgus, Simian), Rhesus macaque
Host HEK293
Konjugat/Tag Unconjugated, HIS
Purity 90%
Citations (1) White R.T., et al., 1992, J. Biol. Chem. 267:9210-9213. (2) Johnson D.M.A., et al., 1984, FEBS Lett. 166:347-351. (3) Sprong T., et al., 2006, Blood 107:4865-4870.
NCBI XP_005587397.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias CFD,Adipsin,PFD,DF,Complement factor D
Versandbedingung Raumtemperatur
Lieferbar
Specificity Rhesus macaque / Cynomolgus
Manufacturer - Category
Protein / Enzymes
Manufacturer - Conjugate / Tag
C-10xHis, Unconjugated
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
26.5 kDa
Manufacturer - Format
Powder
Description
Rhesus macaque / Cynomolgus Complement Factor D, His Tag (CFD-R52H3) is expressed from human 293 cells (HEK293). It contains AA Ile 26 - Ala 253 (Accession # H9EXC1-1). In the region Ile 26 - Ala 253, the AA sequence of Rhesus macaque and Cynomolgus Complement Factor D are homologus.
Background
Complement factor D (CFD) is also known as Adipsin, C3 convertase activator, Properdin factor D (PFD), which contains one peptidase S1 domain and belongs to the peptidase S1 family. CFD / Adipsin cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. CFD / Adipsin is a serine protease that stimulates glucose transport for triglyceride accumulation in fats cells and inhibits lipolysis. Defects in CFD / Adipsin are the cause of complement factor D deficiency which predisposes to invasive meningococcal disease.
Molecule
Complement Factor D
Exp Region
Ile 26 - Ala 253
Characteristics
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.5 kDa. The protein migrates as 25-27 kDa under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
50 mM Tris, 150 mM NaCl, pH8.0
Stability
● -20°C to -70°C for 12 months in lyophilized state;
● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
glycerol

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 1 mg
Lieferbar: In stock
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