ArtNr |
DIM-PME100099-100ug |
Hersteller |
DIMA Biotechnology
|
Menge |
100 ug |
Quantity options |
100 ug
10 ug
50 ug
|
Kategorie |
|
Typ |
Proteins |
Format |
Lyophilized |
Applikationen |
WB |
Specific against |
other |
Host |
HEK293 |
Konjugat/Tag |
HIS |
Purity |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
EGFR, ERBB, ERBB1, HER1, PIG61, mENA |
Versandbedingung |
Raumtemperatur |
Lieferbar |
|
Manufacturer - Type |
Recombinant |
Manufacturer - Category |
ECD Proteins |
Manufacturer - Targets |
EGFR |
Manufacturer - Conjugate / Tag |
C-6xHis Tag |
Molecular Weight |
The protein has a predicted molecular mass of 69.4 kDa after removal of the signal peptide.The apparent molecular mass of EGFR-His is approximately 100-130 kDa due to glycosylation. |
Buffer |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 117 % trehalose is added as protectants before lyophilization. |
Purification |
affinity purification |
Storage |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background |
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. |
Molecular Characterization |
EGFR(Leu25-Ser645) 6xHis tag |
Description |
Recombinant human EGFR Protein with C-terminal 6xHis tag |
Reconstitution |
Reconstitute with deionized water |
Formulation & Reconstitution |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
Usage |
Research use only |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.