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Human TGFBR1 Protein, N-hFc Tag

ArtNr DIM-PME100103-10ug
Hersteller DIMA Biotechnology
Menge 10 ug
Quantity options 100 ug 10 ug 50 ug
Kategorie
Typ Proteins
Format Lyophilized
Applikationen WB
Specific against other
Host HEK293
Konjugat/Tag Fc
Purity The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias AAT5,ACVRLK4,ALK-5,ALK5,ESS1,LDS1,LDS1A,LDS2A,MSSE,SKR4,tbetaR-I,TBR-i,TBRI,TGFR-1
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Type
Recombinant
Manufacturer - Category
ECD Proteins
Manufacturer - Targets
TGFBR1
Manufacturer - Conjugate / Tag
N-Human Fc Tag
Molecular Weight
The protein has a predicted molecular mass of 36.3 kDa after removal of the signal peptide.The apparent molecular mass of hFc-TGFBR1 is approximately 40-53 kDa due to glycosylation.
Buffer
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 117 % trehalose is added as protectants before lyophilization.
Purification
affinity purification
Storage
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background
The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.
Molecular Characterization
hFc(Glu99-Ala330) TGFBR1(Leu34-Leu126)
Description
Recombinant human TGFBR1 Protein with N-terminal Human Fc tag
Reconstitution
Reconstitute with deionized water
Formulation & Reconstitution
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Usage
Research use only

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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