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Human CXCR4 Protein, hFc Tag

ArtNr DIM-PME100834-100ug
Hersteller DIMA Biotechnology
Menge 100 ug
Quantity options 100 ug 10 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Lyophilized
Specific against Human (Homo sapiens)
Host HEK293
Konjugat/Tag Fc
Purity The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias CD184, D2S201E, FB22, HM89, HSY3RR, LAP-3, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM, WHIMS
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Category
ECD Proteins
Manufacturer - Targets
CXCR4
Manufacturer - Conjugate / Tag
C-Human Fc Tag
Molecular Weight
The protein has a predicted molecular mass of 30.5 kDa after removal of the signal peptide. The apparent molecular mass of CXCR4-hFc is approximately 35-55 kDa due to glycosylation.
Buffer
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Purification
affinity purification
Storage
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background
This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Molecular Characterization
CXCR4(Met1-Lys38) hFc(Glu99-Ala330)
Description
Recombinant Human CXCR4 with C-terminal human Fc tag
Reconstitution
Reconstitute with deionized water
Formulation & Reconstitution
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Usage
Research use only

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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