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Human IL13 Protein, hFc Tag

ArtNr DIM-PME100872-100ug
Hersteller DIMA Biotechnology
Menge 100 ug
Quantity options 100 ug 10 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Lyophilized
Specific against Human (Homo sapiens)
Host HEK293
Konjugat/Tag Fc
Purity The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias IL-13,NC30
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Category
ECD Proteins
Manufacturer - Targets
IL13
Manufacturer - Conjugate / Tag
C-Human Fc Tag
Molecular Weight
The protein has a predicted molecular mass of 38.1 kDa after removal of the signal peptide. The apparent molecular mass of IL13-hFc is approximately 35-70 kDa due to glycosylation.
Buffer
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Purification
affinity purification
Storage
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background
This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008]
Molecular Characterization
IL13(Thr21-Leu132) hFc(Glu99-Ala330)
Description
Recombinant human IL13 protein with C-terminal human Fc tag
Reconstitution
Reconstitute with deionized water
Formulation & Reconstitution
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Usage
Research use only

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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