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Human FKBP4 / FKBP52 Protein, His,PA Tag

Human FKBP4 / FKBP52 Protein, His,PA Tag

ArtNr	FK4-H52Q3-500ug
Hersteller	ACROBiosystems
Menge	100 ug x 5
Quantity options	100 ug x 5 50 ug
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Solid
Specific against	Human (Homo sapiens)
Host	HEK293
Konjugat/Tag	Unconjugated
Purity	95%
Citations	(1) Tai P.-K.K., et at., 1992, Science 256:1315-1318. (2) Shim S., et al., 2009, Neuron 64:471-483.
NCBI	AAH01786
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	FKBP4,FKBP52
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Category	Protein
Manufacturer - Conjugate / Tag	C-10xHis & C-PA Tag, Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	55.1 kDa
Manufacturer - Format	Powder
Description	Peptidyl-prolyl cis-trans isomerase FKBP4 (PPIase FKBP4) is also known as immunophilin FKBP52. FKBP4 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP4 has high structural and functional similarity to FK506-binding protein 1A (FKBP1A), but unlike FKBP1A, this protein does not have immunosuppressant activity when complexed with FK506. FKBP4 interacts with interferon regulatory factor-4 and plays an important role in immunoregulatory gene expression in B and T lymphocytes.
Background	Peptidyl-prolyl cis-trans isomerase FKBP4 (PPIase FKBP4) is also known as immunophilin FKBP52. FKBP4 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP4 has high structural and functional similarity to FK506-binding protein 1A (FKBP1A), but unlike FKBP1A, this protein does not have immunosuppressant activity when complexed with FK506. FKBP4 interacts with interferon regulatory factor-4 and plays an important role in immunoregulatory gene expression in B and T lymphocytes.
Molecule	FKBP4
Exp Region	Met 1 - Ala 459
Characteristics	This protein carries a polyhistidine tag at the C-terminus, followed by a PA tag, and has a calculated MW of 55.1 kDa. The reducing (R) protein migrates as 60 kDa in SDS-PAGE.
Endotoxin	1.0 EU per μg
Buffer	50 mM Tris, 100 mM Glycine, pH7.5
Stability	● -20°C to -70°C for 12 months in lyophilized state ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

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FK4-H52Q3-500ug-datasheet.pdf

FK4-H52Q3-500ug-safety-datasheet.pdf