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Canine GITR / TNFRSF18 Protein, His Tag Europäischer Partner

ArtNr GIR-C52H6-1mg
Hersteller ACROBiosystems
Menge 1 mg
Quantity options 100 ug 1 mg
Kategorie
Typ Proteins Recombinant
Format Solid
Specific against Dog (Canine, Canis lupus familiaris)
Host HEK293
Konjugat/Tag Unconjugated, HIS
Purity 90%
Citations (1) Tuyaerts S., et al., 2007, J. Leukoc. Biol. 82:93-105. (2) Chattopadhyay K., et al., 2007, Proc. Natl. Acad. Sci. U.S.A. 104:19452-19457.
NCBI NP_001177673.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias AITR,GITR,TNFRSF18,CD357
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Category
Protein / Immune Checkpoint Proteins
Manufacturer - Conjugate / Tag
C-10xHis, Unconjugated
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
15.8 kDa
Manufacturer - Format
Powder
Description
Canine GITR, His Tag (GIR-C52H6) is expressed from human 293 cells (HEK293). It contains AA Gly 23 - Pro 154 (Accession # D7F619-1).
Background
Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.
Molecule
GITR
Exp Region
Gly 23 - Pro 154
Characteristics
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 15.8 kDa. The protein migrates as 20-25 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
PBS, pH 7.4
Stability
● -20°C to -70°C for 12 months in lyophilized state;
● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 1 mg
Lieferbar: In stock
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