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Animal-Free BAFF/TNFSF13B, Mouse (His)

Animal-Free BAFF/TNFSF13B, Mouse (His)

ArtNr	HY-P700161AF-10ug
Hersteller	MedChem Express
Menge	10 ug
Quantity options	10 ug 1 ea 2 ug 50 ug
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Specific against	other
Purity	95.0
Sequence	MAFQGPEETE QDVDLSAPPA PCLPGCRHSQ HDDNGMNLRN IIQDCLQLIA DSDTPTIRKG TYTFVPWLLS FKRGNALEEK ENKIVVRQTG YFFIYSQVLY TDPIFAMGHV IQRKKVHVFG DELSLVTLFR CIQNMPKTLP NNSCYSAGIA RLEEGDEIQL AIPRENAQIS RNGDDTFFGA LKLL
Citations	[1]Möckel T, et al. B cell activating factor (BAFF): Structure, functions, autoimmunity and clinical implications in Systemic Lupus Erythematosus (SLE). Autoimmun Rev. 2021 Feb;20(2):102736. [2]Gavin AL, et al. DeltaBAFF, an alternate splice isoform that regulates receptor binding and biopresentation of the B cell survival cytokine, BAFF. J Biol Chem. 2003 Oct 3;278(40):38220-8. [3]Yarchoan M, et al. Effects of B cell-activating factor on tumor immunity. JCI Insight. 2020 May 21;5(10):e136417.
Smiles	MAFQGPEETE QDVDLSAPPA PCLPGCRHSQ HDDNGMNLRN IIQDCLQLIA DSDTPTIRKG TYTFVPWLLS FKRGNALEEK ENKIVVRQTG YFFIYSQVLY TDPIFAMGHV IQRKKVHVFG DELSLVTLFR CIQNMPKTLP NNSCYSAGIA RLEEGDEIQL AIPRENAQIS RNGDDTFFGA LKLL
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Animal-Free BAFF/TNFSF13B Protein, Mouse (His),Mouse,E. coli
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Recombinant Proteins
Shipping Temperature	Blue Ice
Storage Conditions	Stored at -20°C for 2 years
Molecular Weight	Approximately 21.56 kDa
Product Description	BAFF/TNFSF13B, is the B cell-activating cytokine belonging to the tumor necrosis factor family. BAFF is involved in cancer immunity and is mainly expressed in myeloid cells. Its overexpression can lead to autoimmune diseases such as systemic lupus erythematosus (SLE). In addition, BAFF is also involved in adipogenesis, atherosclerosis, neuroinflammatory process and ischemia/reperfusion (I/R) injury [1]. Mouse BAFF protein has two glycosylated domains and one transmembrane domain (48-68 a.a.), and can be cleaved into membrane-type peptide fragments and soluble peptide fragments. Animal-Free BAFF/TNFSF13B Protein, Mouse (His) is the extracullar part of BAFF protein (A127-L309), produced in HEK293 cells with C-terminal His-tag.This product is for cell culture use only.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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