Product Description |
NOTCH1 protein is a receptor for the ligands JAG1, JAG2 and DLL1 and is critical for cell fate decisions. Upon ligand activation, NICD forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes in the cleavage site enhancer. NOTCH1 Protein, Human (HEK293, His-Avi) is the recombinant human-derived NOTCH1 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of NOTCH1 Protein, Human (HEK293, His-Avi) is 508 a.a., with molecular weight of 70-80 kDa. |