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Human IDH1 Protein (IDH-HE101)

Human IDH1 Protein (IDH-HE101)

ArtNr	IDH-HE101-500UG
Hersteller	KactusBio
Menge	500 ug
Quantity options	100 ug 500 ug
Kategorie	Oncology By Cell Type Carcinoma Glioma Hematology Leukemia Lymphoma Sarcoma Peptides & Proteins Recombinant Proteins Myelofibrosis Astrocytoma By Organ Brain Cancer Blastom
Typ	Proteins Recombinant
Format	Liquid
Specific against	Human (Homo sapiens)
Host	E.coli
Konjugat/Tag	HIS
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Formula	Supplied as 0.22μm filtered solution in 50mM Tris, 200mM NaCl, 1mM DTT, 10% Glycerol (pH 7.5).
Dry ice	Yes
Sequence	Ser2-Leu414
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	IDH,IDH1,IDPc,PICD,IDP,DCD,IDH,Isocitrate dehydrogenase,IDCD
Versandbedingung	Trockeneis
Lieferbar
Manufacturer - Type	Recombinant Protein
Manufacturer - Targets	IDH1
Manufacturer - Conjugate / Tag	C-His
Shipping Temperature	Shipped with dry ice.
Storage Conditions	Valid for 12 months from date of receipt when stored at -80°C.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Molecular Weight	The protein has a predicted MW of 47.35 kDa same as Bis-Tris PAGE result.
Description	Recombinant Human IDH1 Protein is expressed from E.coli with His tag at the C-Terminus.It contains Ser2-Leu414.
Background	Isocitrate dehydrogenase (IDH) is a metabolic enzyme that converts isocitrate to α-ketoglutarate (α-KG). Genetic gain-of-function mutations in IDH1 and IDH2 confer a neomorphic activity that allow reduction of α -KG to (R)-2- hydroxyglutarate, the accumulation of which results in the development of cancers like low grade gliomas and leukemia.Isocitrate dehydrogenase 1 (IDH1) is the most frequently mutated metabolic gene in cancer.
Endotoxin	Less than 1 EU per μg by the LAL method.
Formulation	Supplied as 0.22μm filtered solution in 50mM Tris, 200mM NaCl, 1mM DTT, 10% Glycerol (pH 7.5).
Biotinylated	no

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

IDH-HE101-500UG-datasheet.pdf

IDH-HE101-500UG-safety-datasheet.pdf