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Human IFN gamma R1/IFNGR1 Protein (IFN-HM2GR)

Human IFN gamma R1/IFNGR1 Protein (IFN-HM2GR)

ArtNr	IFN-HM2GR-500UG
Hersteller	KactusBio
Menge	500 ug
Quantity options	100 ug 500 ug
Kategorie	Oncology By Cell Type Peptides & Proteins Recombinant Proteins Melanom
Typ	Proteins Recombinant
Format	Lyophilized
Specific against	Human (Homo sapiens)
Host	HEK293
Konjugat/Tag	C-hFc
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Formula	Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Sequence	Glu18-Gly245
NCBI	AAH05333
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	IFN-gamma-R1,CDw119,CD119,IFNGR1,IFNGR,AVP,FLJ45734,IFN-gamma R1,IFN-gR1,type 2,IFNγ,IFNγR1,IFN γR1,IFNγ R1,IFN γ R1
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Recombinant Protein
Manufacturer - Targets	IFN gamma R1/IFNGR1
Shipping Temperature	Shipped at ambient temperature.
Storage Conditions	-20 to -80°C for 24 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Molecular Weight	The protein has a predicted MW of 52.4 kDa. Due to glycosylation, the protein migrates to 60-75 kDa based on Bis-Tris PAGE result.
Description	Recombinant Human IFN gamma R1/IFNGR1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Glu18-Gly245.
Background	IFN-gamma and one of its receptor subunits, IFNGR1, are translocated to the nucleus, together with STAT1alpha as one macromolecular complex, via the classical importin-dependent pathway.Put IFN-gamma and its receptor subunit, IFNGR1, in direct contact with the promoter region of IFN-gamma-activated genes with associated increased activity, thus suggesting a transcriptional/cotranscriptional role for IFN-gamma/IFNGR1 as well as a possible role in determining the specificity of IFN-gamma action.
Endotoxin	Less than 1 EU per μg by the LAL method.
Formulation	Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Biotinylated	no

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

IFN-HM2GR-500UG-datasheet.pdf

IFN-HM2GR-500UG-safety-datasheet.pdf