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Mouse IgG1 Fc Protein, Tag Free (MALS verified)

Mouse IgG1 Fc Protein, Tag Free (MALS verified)

ArtNr	IG1-M5208-200ug
Hersteller	ACROBiosystems
Menge	200 ug
Quantity options	250 ug x 4 200 ug
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Solid
Specific against	Mouse (Murine, Mus musculus)
Host	HEK293
Konjugat/Tag	Unconjugated
Purity	95%
Citations	(1) Medinger M, Tzankov A,et al.( 2010), J Clin Immunol. 30 Suppl 1:S9-14.
NCBI	AAK53870.1
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	IgG1
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Category	Protein / Other Recombinant Proteins
Manufacturer - Conjugate / Tag	Native, Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	24.3 kDa
Manufacturer - Format	Powder
Description	Mouse IgG Fc, Tag Free (IG1-M5208) is expressed from human 293 cells (HEK293). It contains AA Val 111 - Lys 324 (Accession # AAK53870.1).
Background	Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.
Molecule	IgG1 Fc
Exp Region	Val 111 - Lys 324
Characteristics	This protein carries no "tag". The protein has a calculated MW of 24.3 kDa. The protein migrates as 28-30 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Stability	● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

IG1-M5208-200ug-datasheet.pdf

IG1-M5208-200ug-safety-datasheet.pdf