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Human IgG4 Fc Protein, Tag Free (MALS & SPR verified)

Human IgG4 Fc Protein, Tag Free (MALS & SPR verified)

ArtNr	IG4-H5205-1mg
Hersteller	ACROBiosystems
Menge	1 mg
Quantity options	1 mg 200 ug
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Solid
Specific against	Human (Homo sapiens)
Host	HEK293
Konjugat/Tag	Unconjugated
Purity	95%
Citations	(1) Frangione B., et al., 1969, Nature 221:145-148. (2) Kristiansen T.Z., et al., 2004, Mol. Cell. Proteomics 3:715-728. (3) Chen R., et al., 2009, J. Proteome Res. 8:651-661.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	IGHG4
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Category	Protein / Other Recombinant Proteins
Manufacturer - Conjugate / Tag	Native, Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	25.8 kDa
Manufacturer - Format	Powder
Description	Human IgG4 Fc, Tag Free (IG4-H5205) is expressed from human 293 cells (HEK293). It contains AA Glu 99 - Lys 327 (Accession # P01861).
Background	Immunoglobulin G4 (IgG4) is a member of many immunoglobulin G developed and secreted by effective B cells. In wake of cutting by pepsin, IgG is divided into two F(ab)s with one antigen binding site and a high conserved Fc segment. The Fc segment bears a highly conserved N-glycosylation site. Ig gamma-4 chain Fc region contains two constant regions of IgG4 H chain (CH2, CH3).
Molecule	IgG4 Fc
Exp Region	Glu 99 - Lys 327
Characteristics	This protein carries no "tag". The protein has a calculated MW of 25.8 kDa. The protein migrates as 30-33 kDa under reducing (R) condition, and 29 kDa and 55-60 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	Tris with Glycine, Arginine and NaCl, pH7.5
Stability	● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

IG4-H5205-1mg-datasheet.pdf

IG4-H5205-1mg-safety-datasheet.pdf