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Mouse IgG2a Fc Protein, Tag Free (MALS verified)

Mouse IgG2a Fc Protein, Tag Free (MALS verified)

ArtNr	IGA-M5207-1mg
Hersteller	ACROBiosystems
Menge	1 mg
Quantity options	1 mg 200 ug
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Solid
Specific against	Mouse (Murine, Mus musculus)
Host	HEK293
Konjugat/Tag	Unconjugated
Purity	90%
Citations	(1) Sikorav J.-L., et al., 1980, Nucleic Acids Res. 8:3143-3155. (2) Ollo R., et al., 1981, Proc. Natl. Acad. Sci. U.S.A. 78:2442-2446.
NCBI	CAC20702
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	IgG2A
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Category	Protein / Other Recombinant Proteins
Manufacturer - Conjugate / Tag	Native, Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	26.4 kDa
Manufacturer - Format	Powder
Description	Mouse IgG2a Fc, Tag Free (IGA-M5207) is expressed from human 293 cells (HEK293). It contains AA Glu 98 - Lys 330 (Accession # CAC20702).
Background	Immunoglobulin G2 (IgG2) is a member of many immunoglobulin G developed and secreted by effective B cells. In wake of cutting by pepsin, IgG is divided into two F(ab)s with one antigen binding site and a high conserved Fc segment. The Fc segment bears a highly conserved N-glycosylation site. There are two members of IgG2: IgG2a and IgG2b. It was found that IgG2a was superior to IgG1 in activating complement. The glycosylation of the circulating immunoglobulin-γ (IgG) antibody molecules changes in rheumatoid arthritis.
Molecule	IgG2a Fc
Exp Region	Glu 98 - Lys 330
Characteristics	This protein carries no "tag". The protein has a calculated MW of 26.4 kDa. The protein migrates as 30-35 kDa under reducing (R) condition, and 55-60 kDa under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5
Stability	● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

IGA-M5207-1mg-datasheet.pdf

IGA-M5207-1mg-safety-datasheet.pdf