ArtNr |
IL1-HM4L2B-100UG |
Hersteller |
KactusBio
|
Menge |
100 ug |
Quantity options |
100 ug
500 ug
|
Kategorie |
|
Typ |
Proteins Recombinant |
Format |
Lyophilized |
Specific against |
Human (Homo sapiens) |
Host |
HEK293 |
Konjugat/Tag |
HIS, Avi |
Purity |
> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC |
Formula |
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Sequence |
Asp20-Arg335 |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
IL-1 R6, IL-1 Rrp2, IL1RL2, IL1Rrp2, IL1RRP2, IL-36R |
Lieferbar |
|
Manufacturer - Product Type |
Recombinant Protein |
Description |
Recombinant Biotinylated Human IL-1 Rrp2/IL-1 R6 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Asp20-Arg335. |
Background |
The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL‑1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R6), IL-18 Rb (AcPL/IL-1 R7), IL-1RAPL‑1 (TIGIRR‑2/IL‑1 R8), and TIGIRR-1 (IL-1 R9). IL1RL2 is a receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways. |
Endotoxin |
Less than 1 EU per μg by the LAL method. |
Molecular Weight |
The protein has a predicted MW of 39.1 kDa. Due to glycosylation, the protein migrates to 55-75 kDa based on Bis-Tris PAGE result. |
Target |
IL-1 Rrp2/IL-1 R6 |
Manufacturer - Tag |
C-His-Avi |
Stability and Storage |
-20 to -80°C for 12 months as supplied from date of receipt; -80°C for 3-6 months after reconstitution; 2-8°C for 2-7 days after reconstitution; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Biotinylated |
yes |
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