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Human IL-7 R alpha / CD127 Protein (I66T, V138I), Mouse IgG2a Fc Tag Europäischer Partner

ArtNr IL7-H5258-100ug
Hersteller ACROBiosystems
Menge 100 ug
Quantity options 100 ug 500 ug x 2
Kategorie
Typ Proteins Recombinant
Format Solid
Specific against Human (Homo sapiens)
Host HEK293
Isotype IgG2a
Konjugat/Tag Unconjugated, C-mFc
Purity 90%
Citations (1) Noguchi M., et al., 1994, Science 262 (5141): 1877-80. (2) Kroemer RT., et al., 1997, Protein Eng. 9 (12): 1135-42. (3) McElroy C.A., et al., 2009, Structure 17:54-65.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias IL7Ra,CD127
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Category
Protein / Bio-Markers & CD Antigens
Manufacturer - Conjugate / Tag
C-mFc(mIgG2a), Unconjugated
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
52.0 kDa
Manufacturer - Format
Powder
Description
Human IL-7 R alpha, Mouse IgG2a Fc Tag (IL7-H5258) is expressed from human 293 cells (HEK293). It contains AA Glu 21 - Gly 236 (Accession # P16871-1 (I66T, V138I)).
Background
Interleukin-7 receptor subunit alpha (IL7Ra) is also known as CD antigen CD127, which belongs to the type I cytokine receptor family and type 4 subfamily. IL7Ra /CD127 contains 1 fibronectin type-III domain. IL7Ra /CD127 is expressed on various cell types, including naive and memory T cells and many others. IL7Ra /CD127 is receptor for interleukin-7 and also acts as a receptor for thymic stromal lymphopoietin (TSLP). The IL7 receptor is a heterodimer of IL7R and IL2RG. The TSLP receptor is a heterodimer of CRLF2 and IL7R.
Molecule
IL-7 R alpha
Exp Region
Glu 21 - Gly 236
Characteristics
This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 52.0 kDa. The protein migrates as 75-95 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
Tris with Glycine,  Arginine and NaCl,  pH7.5
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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