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Human IL-17 RC Protein, Fc Tag (MALS verified)

Human IL-17 RC Protein, Fc Tag (MALS verified)

ArtNr	ILC-H5259-1mg
Hersteller	ACROBiosystems
Menge	1 mg
Quantity options	100 ug 1 mg
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Solid
Specific against	Human (Homo sapiens)
Host	HEK293
Konjugat/Tag	Unconjugated, Fc
Purity	95%
Citations	(1) Wright JF. J Immunol. 2008 Aug 15;181(4):2799-805. (2) Toy D. J Immunol. 2006 Jul 1;177(1):36-9. (3) Kuestner RE. J Immunol. 2007 Oct 15;179(8):5462-73.
NCBI	NP_703190.2
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	IL-17 RC,IL-17RC,IL17Rhom,IL-17 receptor C,IL-17RL,ZcytoR14
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Category	Protein / Bio-Markers & CD Antigens
Manufacturer - Conjugate / Tag	C-Fc, Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	75.9 kDa
Manufacturer - Format	Powder
Description	Human IL-17 RC, Fc Tag (ILC-H5259) is expressed from human 293 cells (HEK293). It contains AA Leu 21 - His 465 (Accession # NP_703190.2).
Background	Interleukin-17 receptor C (IL-17 RC), also known as IL17Rhom, IL-17RL, is the receptor for IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RA. IL-17A activity is inhibited by IL-17RA, IL-17F is inhibited by IL-17RC, and a combination of soluble IL-17RA/IL-17RC receptors is required for inhibition of the IL-17F/IL-17A activity. Furthermore, activation of IL17RC can lead to the induction of expression of inflammatory chemokines and cytokines such as CXCL1.
Molecule	IL-17 RC
Exp Region	Leu 21 - His 465
Characteristics	This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 75.9 kDa. The protein migrates as 90-115 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	PBS, pH7.4
Stability	● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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ILC-H5259-1mg-datasheet.pdf

ILC-H5259-1mg-safety-datasheet.pdf