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Human IL-17 RE (155-454) Protein, Fc Tag Europäischer Partner

ArtNr ILE-H5256-100ug
Hersteller ACROBiosystems
Menge 100 ug
Quantity options 100 ug 200 ug x 5
Kategorie
Typ Proteins Recombinant
Format Solid
Specific against Human (Homo sapiens)
Host HEK293
Konjugat/Tag Unconjugated, Fc
Purity 95%
Citations (1) Song X. Nat Immunol. 2011. 12(12):1151-8. (2) Ramirez-Carrozzi V. Nat Immunol. 2011. 12(12):1159-66. (3) Pfeifer P. Am J Respir Cell Mol Biol. 2013. 48(4):415-21.
NCBI NP_705613.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias IL-17 RE,IL17RE,IL-17RE,IL-17 receptor E
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Category
Protein / Bio-Markers & CD Antigens
Manufacturer - Conjugate / Tag
C-Fc, Unconjugated
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
60.5 kDa
Manufacturer - Format
Powder
Description
Human IL-17 RE (155-454), Fc Tag (ILE-H5256) is expressed from human 293 cells (HEK293). It contains AA Thr 155 - His 454 (Accession # Q8NFR9-1).
Background
Interleukin-17 receptor E (IL-17 RE) is an orphan receptor of the IL-17 receptor family, also known as UNQ3056, PRO9877, IL-17 Receptor E. IL-17RE is known to be expressed in the pancreas, brain, and prostate. IL-17RE is a receptor specific to IL-17C and has an essential role in host mucosal defense against infection. IL-17C functioned in a unique autocrine manner, binding to a receptor complex consisting of the receptors IL-17RA and IL-17RE, which was preferentially expressed on tissue epithelial cells. Some data identify IL-17RE as a receptor of IL-17C that regulates early innate immunity to intestinal pathogens.
Molecule
IL-17 RE
Exp Region
Thr 155 - His 454
Characteristics
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 60.5 kDa. The protein migrates as 66-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
Tris with Glycine,  Arginine and NaCl,  pH7.5
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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