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Human IL-1 RAcP / IL-1 R3 Protein, Fc Tag Europäischer Partner

ArtNr ILP-H5256-1mg
Hersteller ACROBiosystems
Menge 200 ug x 5
Quantity options 100 ug 200 ug x 5
Kategorie
Typ Proteins Recombinant
Format Solid
Specific against Human (Homo sapiens)
Host HEK293
Konjugat/Tag Unconjugated, Fc
Purity 95%
Citations (1) Huang J., et al., 1997, Proc. Natl. Acad. Sci. U.S.A. 94:12829-12832. (2) Jensen L.E., et al., 2000, J. Immunol. 164:5277-5286. (3) Smith D.E., et al., 2003, Immunity 18:87-96.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias IL1RAP,IL-1RAcP,C3orf13,IL1R3
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Category
Protein / Cytokines&Growth Factors
Manufacturer - Conjugate / Tag
C-Fc, Unconjugated
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
65.7 kDa
Manufacturer - Format
Powder
Description
Human IL-1 RAcP, Fc Tag (ILP-H5256) is expressed from human 293 cells (HEK293). It contains AA Ser 21 - Glu 359 (Accession # Q9NPH3).
Background
Interleukin-1 receptor accessory protein (IL1RAP or IL-1RAcP) is also known as Interleukin-1 receptor 3 (IL-1R-3 or IL-1R3), C3orf13, which belongs to the interleukin-1 receptor family. IL1RAP contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RAP is detected in liver, skin, placenta, thymus and lung. IL-1R3 / IL1RAP is coreceptor with IL1R1, associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways.
Molecule
IL-1 RAcP
Exp Region
Ser 21 - Glu 359
Characteristics
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 65.7 kDa. The protein migrates as 70-90 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
50 mM Tris, 100 mM Glycine, pH7.5
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 200 ug x 5
Lieferbar: In stock
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